Cell and Animal Studies Could Enable Development of Effective Drugs for Addiction


The Scripps Research Institute's team of scientists has explored a combination of cell and animal studies that enable the development of effective drugs for addiction with fewer side effects.

The Journal of Biological Chemistry published the study, which features one active compound, known as 6'-GNTI, that targets the kappa opioid receptor (KOR). KOR plays a role in the release of dopamine, which is the focus for drug discovery efforts aimed at treating addiction, and impulse and personality disorders.

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Federal Programs Related to - Mental Health, Substance Abuse Programs, General/other

Programs that provide preventive, diagnostic and treatment services as well as transitional support for people who have a physical and/or psychological dependency on tobacco, alcohol and/or other drugs or who suffer from acute or chronic mental or emotional disturbances or are having problems coping with daily living.

Federal Programs Related to - Substance Abuse

Programs that provide preventive, diagnostic and inpatient, outpatient and residential treatment services as well as transitional support for people who have a physical and/or psychological dependency on tobacco, alcohol and/or other drugs. Addictions; Alcohol Rehabilitation; Alcoholism; Alcohol-Related Triage; Chemical Abuse; Chemical Dependency; Drug Addiction; Drug Habit; Drug Rehabilitation; Drug-Related Triage; Maintenance Treatment; Medication Abuse; Narcotic Habit; Perinatal Alcohol Treatment; Perinatal Drug Treatment; Perinatal Substance Abuse Treatment; Public Inebriate Transportation; Substance Abuse Rehabilitation




Social Entrepreneurship
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Increasing the Diversity of Social Entrepreneurs in the U.S.


Increasing the diversity of social entrepreneurs in the U.S.

One of the most significant challenges to social entrepreneurship and innovation is ensuring a diversity of approaches and participants in the movement. To truly deliver meaningful social change the leaders of the effort must share perspectives of the challenges faced by communities across the U.S. that can most appropriately come from members of those communities. Ashoka, through its All America initiative seeks to increase the diversity of social entrepreneurship practitioners.




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